The MIEBO experience

IN GOBI AND MOJAVE PIVOTAL TRIALS:

IN THE KALAHARI STUDY2:

Pictogram conveying approx. 9.4 out of 10

Most patients (~94%) were considered compliant with dosing throughout the study

Tear and plus sign inside droplet icon

Only ~5% of patients (n = 10) used adjunctive artificial tears/mineral oil, as permitted, after Week 4

The majority of patients2‡:

  • checkmark icon

    Were satisfied with MIEBO treatment

  • checkmark icon

    Found MIEBO comfortable

  • checkmark icon

    Said MIEBO was easy to administer

SD, standard deviation.

*Questionnaire was given on Day 1 of the GOBI and MOJAVE studies. Mean pooled comfort score was 8.0 for MIEBO and 8.4 for saline (scale of 0-10, 0 = not comfortable and 10 = very comfortable). 81% of patients treated with MIEBO reported a score of 7 or higher.1

Defined as administration of 80% to 120% of the expected doses.2

Mean Visual Analog Scale (VAS) score (SD) was assessed at Week 52. Respondents rated MIEBO with the following scores (scale of 0-10): satisfaction, 8.0 (2.3); comfort, 8.4 (2.1); ease of administration, 8.9 (1.9).2

What to expect

Slider comparing smaller drop size of MIEBO to larger drop size of formulations containing water

AQUEOUS FORMULATION

Not actual size.

Aqueous formulations have a typical drop size of ~30-50 μL3

Slider comparing smaller drop size of MIEBO to larger drop size of formulations containing water

MIEBO

Not actual size.

The small drop size (11 μL) means MIEBO may feel different from formulations containing water3

There may be no ocular sensation or blink reflex upon instillation4

MIEBO dropper bottle

Not actual size.

One drop per eye, QID dosing5

Preservative free and provided
in a convenient multidose bottle (1-month supply)3,5

How to use MIEBO

MIEBO should not be administered while wearing contact lenses. Contact lenses should be removed before use and for at least 30 minutes after administration of MIEBO.5

CORRECTLY IDENTIFY MIEBO

Ensure you get the right MIEBO when searching online or in an electronic medical/health record (EMR/EHR) system.

Remember: “i before e, to treat DED.”

Storage

MIEBO should be stored at room temperature: 15-25 °C (59-77 °F). After opening, MIEBO can be used until the expiration date on the bottle.5

QID, 4 times daily.

 
 
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*Required fields.

By submitting your information, you consent to receive communications containing information and educational resources about MIEBO, as well as other communications from Bausch + Lomb. By submitting your information, you confirm that you have read and agree with the terms of our Privacy Policy and Legal Notice.

INDICATION

MIEBO® (perfluorohexyloctane ophthalmic solution) is indicated for the treatment of the signs and symptoms of dry eye disease.

IMPORTANT SAFETY INFORMATION

  • MIEBO should not be administered while wearing contact lenses. Contact lenses should be removed before use and for at least 30 minutes after administration of MIEBO
  • Instruct patients to instill one drop of MIEBO into each eye four times daily
  • The safety and efficacy in pediatric patients below the age of 18 have not been established
  • The most common ocular adverse reaction was blurred vision (1% to 3% of patients reported blurred vision and conjunctival redness)

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

References: 1. Data on file. Bausch & Lomb, Inc. 2. Protzko EE, Segal BA, Korenfeld MS, Krösser S, Vittitow JL. Long-term safety and efficacy of perfluorohexyloctane ophthalmic solution for the treatment of patients with dry eye disease: the KALAHARI study. Cornea. 2024;43(9):1100-1107. doi:10.1097/ICO.0000000000003418 3. Sheppard JD, Nichols KK. Dry eye disease associated with meibomian gland dysfunction: focus on tear film characteristics and the therapeutic landscape. Ophthalmol Ther. 2023;12(3):1397-1418. doi:10.1007/s40123-023-00669-1 4. Schmidl D, Bata AM, Szegedi S, et al. Influence of perfluorohexyloctane eye drops on tear film thickness in patients with mild to moderate dry eye disease: a randomized controlled clinical trial. J Ocul Pharmacol Ther. 2020;36(3):154-161. doi:10.1089/jop.2019.0092 5. MIEBO. Prescribing Information. Bausch & Lomb, Inc.

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INDICATION AND IMPORTANT
SAFETY INFORMATION

INDICATION

MIEBO® (perfluorohexyloctane ophthalmic solution) is indicated for the treatment of the signs and symptoms of dry eye disease.

IMPORTANT SAFETY INFORMATION

  • MIEBO should not be administered while wearing contact lenses. Contact lenses should be removed before use and for at least 30 minutes after administration of MIEBO
  • Instruct patients to instill one drop of MIEBO into each eye four times daily
  • The safety and efficacy in pediatric patients below the age of 18 have not been established
  • The most common ocular adverse reaction was blurred vision (1% to 3% of patients reported blurred vision and conjunctival redness)

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

Click here for full prescribing Information for MIEBO.